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Silent Infarcts in Children With Sickle Cell Anemia and Abnormal Cerebral Artery Velocity Arch Neurol 58:2017-2021, Pegelow,C.H.,et al, 2001 See this aricle in Pubmed Article Abstract Transfusion therapy lowers the risk for new silent infarct or stroke for children having both abnormal TCD ultrasonographic velocity and silent infarct. However, those with both abnormalities who are not provided transfusion therapy are at higher risk for developing a new silent infarct or stroke than are those whose initial MRI showed no abnormality. The finding of a silent infarct reinforces the need for TCD ultrasonographic screening and consideration of transfusion therapy if the abnor malities are seen. Similarly, elevated TCD ultrasonographic velocity warrants MRI of the brain because children with both abnormalities seem to be at increased risk for developing new silent infarct or stroke.

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(click to filter results - removes previous filter) asymptomatic blood transfusion cerebral infarction cerebrovascular accident cerebrovascular accident,infancy and childhood cerebrovascular accident,prevention of cerebrovascular accident,silent children doppler doppler,transcranial MRI MRI,abnormal prevention of neurologic disorders sickle cell disease

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